This research examines the dynamic relationship between inflation and GDP growth across a global sample of countries from 2000 to 2023. Utilizing panel data analysis, we explore how inflation influences GDP growth and vice versa, considering economic heterogeneity across developed and developing nations. The study employs a Vector Autoregression (VAR) model to capture the dynamic interactions and Granger causality tests to determine directional relationships. Findings suggest a negative short-term relationship between inflation and GDP growth in most economies, with variations based on economic structure and policy frameworks. The results have implications for monetary policy and economic stabilization strategies