The integration of smart wearable technologies with artificial intelligence (AI) offers transformative potential for monitoring health parameters following vaccination. As global immunization efforts accelerate in response to pandemics and emerging infections, the need for proactive, real-time health monitoring has intensified. This paper explores how wearable devices, combined with AI algorithms, can track post-vaccine symptoms and identify early warning signs of adverse events. Using a combination of physiological data such as heart rate variability, skin temperature, sleep patterns, and reported symptoms, the system provides continuous health surveillance tailored to each individual. Overall, this research highlights the potential of wearable-AI integration to enhance post-vaccination safety, empower patients with insights, and assist public health systems in managing immunization programs more effectively.