Abstract The global supply chain (GSC) has become increasingly complex due to factors such as globalization, technological advancements, and fluctuating consumer demand. However, recent disruptions like natural disasters, geopolitical tensions, and the COVID-19 pandemic have exposed vulnerabilities within the system. This study aims to explore the strategies used by organizations to optimize their supply chain resilience, mitigate risks, and recover quickly from disruptions. Through the use of quantitative analysis, including case studies and statistical modeling, the research identifies best practices in risk management, supply chain diversification, and real-time monitoring. The study will also propose frameworks for organizations to build agility and flexibility into their supply chains, ensuring they can sustain operations and meet consumer demands despite unforeseen challenges