Climate change has emerged as one of the most significant environmental challenges affecting both wildlife and domesticated mammals worldwide. Rising temperatures, altered rainfall patterns, increasing frequency of heat waves, drought, humidity fluctuations, and extreme weather events have substantially influenced the health, physiology, productivity, and behaviour of domestic mammals. Hapur district of Uttar Pradesh, characterized by intensive agriculture, dairy farming, and rapid urbanization, has experienced noticeable climatic variations over recent decades. Cattle, dogs, and horses, which play important economic, social, and ecological roles in the district, are increasingly exposed to heat stress, water scarcity, nutritional deficiencies, disease outbreaks, and reduced reproductive performance. The present study investigates the impact of climate change on cows, dogs, and horses in Hapur through a comprehensive analytical review of recent scientific literature and regional environmental conditions. The findings indicate that increasing ambient temperatures significantly affect physiological responses, feed intake, milk production, reproductive efficiency, work performance, immunity, and disease susceptibility. The study further highlights adaptive management strategies including improved housing, nutritional supplementation, heat stress mitigation, veterinary surveillance, and climate-resilient livestock management. The study concludes that integrated adaptation measures are essential for protecting mammalian health, improving livestock productivity, and ensuring sustainable rural development under changing climatic conditions.