Nosocomial infections are defined as new infections, either localized or systemic, that occur in patients receiving medical care in hospitals or other healthcare settings. These infections are a major cause of death and
increased morbidity among hospitalized patients and healthcare workers. This study investigated the factors affecting nurses' attitudes and practices regarding the prevention of nosocomial infections. Utilizing a descriptive survey research design and purposive sampling of 260 respondents, the study found that while nearly all clinical nurses at the surveyed hospital had sufficient knowledge about preventing nosocomial infections, not all applied this knowledge. Although 70% were aware of prevention methods, only 74.6% consistently washed their hands after every procedure. Additionally, 95% of respondents reported that personal
protective equipment (PPE) was not always available in adequate amounts for all healthcare workers, highlighting the importance of resource availability in preventing nosocomial infections. Furthermore, 76.4% of respondents did not view handwashing after each procedure as a waste of time, indicating that time constraints also influence infection prevention practices. In summary, the study found that while most respondents had good knowledge of nosocomial infection prevention, several factors hindered their ability to implement effective practices.