The present study was conducted to assess the effectiveness of a structured teaching program (STP) on knowledge regarding cord blood banking among final-year students in selected colleges at Aluva. The objectives were to assess the existing knowledge on cord blood banking, evaluate the effectiveness of the STP, and determine the association between post-test knowledge and selected demographic variables. Pre-Experimental one-group pre-test posttest design was adopted. The study was conducted among 40 final-year students from Union Christian College, Aluva, selectedthroughnon-probability convenience sampling. Data were collected on 24th and 25th June 2025 using a structured knowledge questionnaire developed by the investigator. The collected data were analyzed using descriptive and inferential statistics. The findings revealed that none of the students had excellent knowledge in the pretest; 40% had mild knowledge and 60% had moderate knowledge. The mean post- test score was significantly higher than the mean pre-test score, indicating that the structured teaching program was effective in improving the students’ knowledge regarding cord blood banking. There was no significant association between post-test knowledge scores and selected demographic variables. The study concludes that structured teaching programs are effective educational strategies to enhance awareness among nursing students on emerging healthcare topics like cord blood banking. ―Education is the most powerful which you can use to change the world.‖-Nelson Mandela