Diabetes mellitus is a chronic disease which is pointed by the higher levels of blood glucose from a shortcoming in insulin production, insulin action or both. The importantcharacteristicsincludeHyperglycae mia, hyperlipidaemia and oxidative stress which may be a huge risk for the creation of complications of Diabetes. This is said to be reduced by the administration of Aloe Vera in several forms and methods. Studies have been used to prove an anti-hyperglycaemic and anti-hyperlipidaemia effect of the Aloe Vera when administered in the humans and rats affected by DM. This literature review paper systematically compiles the research papers that provide data about the crucial effect of Aloe Vera in the Diabetes mellitus